In OPTIMAL-STROKE, a systolic target below 120 mm Hg reduced major cardiovascular events versus below 140, with a renal-function trade-off.

Interim AvacoStar results found more liver abnormalities with avacopan, but rates were low; the safety study remains ongoing through 2030.

A yoga therapist recommends guided yoga nidra for relaxation and sleep. Here is what the practice involves, what the report says and what remains uncertain.

A Sixty and Me essay remembers Earl, an Arizona farmer and self-taught pilot, and reflects on experience, curiosity and assumptions about expertise.

A JAX study finds age-related inflammation and scarring signals concentrated in the aortic valves and root of mouse hearts.